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Ketogenic low-carbohydrate diets have no metabolic advantage over nonketogenic low-carbohydrate diets.
DESIGN:
Twenty adults [body mass index (in kg/m(2)): 34.4 +/- 1.0] were randomly assigned to the KLC (60% of energy as fat, beginning with approximately 5% of energy as carbohydrate) or NLC (30% of energy as fat; approximately 40% of energy as carbohydrate) diet. During the 6-wk trial, participants were sedentary, and 24-h intakes were strictly controlled.
RESULTS:
Mean (+/-SE) weight losses (6.3 +/- 0.6 and 7.2 +/- 0.8 kg in KLC and NLC dieters, respectively; P = 0.324) and fat losses (3.4 and 5.5 kg in KLC and NLC dieters, respectively; P = 0.111) did not differ significantly by group after 6 wk. Blood beta-hydroxybutyrate in the KLC dieters was 3.6 times that in the NLC dieters at week 2 (P = 0.018), and LDL cholesterol was directly correlated with blood beta-hydroxybutyrate (r = 0.297, P = 0.025). Overall, insulin sensitivity and resting energy expenditure increased and serum gamma-glutamyltransferase concentrations decreased in both diet groups during the 6-wk trial (P < 0.05). However, inflammatory risk (arachidonic acid:eicosapentaenoic acid ratios in plasma phospholipids) and perceptions of vigor were more adversely affected by the KLC than by the NLC diet.
CONCLUSIONS:
KLC and NLC diets were equally effective in reducing body weight and insulin resistance, but the KLC diet was associated with several adverse metabolic and emotional effects. The use of ketogenic diets for weight loss is not warranted.
https://www.ncbi.nlm.nih.gov/pubmed/16685046
View Diet Calendar, 05 September 2019:
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3102 kcal
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Fat: 106.41g | Prot: 180.20g | Carbs: 405.14g.
Breakfast: Pure Protein Chocolate Deluxe High Protein Bar (Small), Pears , Quest Chocolate Chip Cookie Dough Protein Bar, Chobani vanilla greek yogurt, Pepperidge Farm German Chocolate 3-layer Cake, Casey's Bacon Breakfast Pizza. Lunch: Pumpkin Cake with Icing, Winchell's Chocolate Cake Donut - Chocolate Iced, 1% Fat Milk, Quest Chocolate Sprinkled Doughnut Protein Bar, Plum, Peach. Dinner: Kraft 3 Cheese Mexicana Shredded Cheese, Great Value Enriched Hamburger Buns, Field Pork Burger, Oranges, Bell Plantation PB2 Powdered Peanut Butter, Chobani vanilla greek yogurt. Snacks/Other: Mighties Kiwi, Quest Chocolate Brownie Protein Bar. more...
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3903 kcal
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Exercise:
Running (jogging) - 5/mph - 35 minutes, Sleeping - 7 hours and 40 minutes, Sitting - 8 hours, Weight Training (moderate) - 1 hour and 20 minutes, Bicycling (leisurely) - <10/mph - 2 hours and 35 minutes, Resting - 3 hours and 50 minutes. more...
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